Cx43-mediated hyphal folding counteracts phagosome integrity loss during fungal infection

Cx43-mediated hyphal folding counteracts phagosome integrity loss during fungal infection

ABSTRACT Phagolysosomes are crucial organelles during the elimination of pathogens by host cells. The maintenance of their membrane integrity is vital during stressful conditions, such as during Candida albicans infection. As the fungal hyphae grow, the phagolysosome membrane expands to ensure that...

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Bibliographic Details
Main Authors: Beatriz Cristovao, Lisa Rodrigues, Steve Catarino, Monica Abreu, Teresa Gonçalves, Neuza Domingues, Henrique Girao
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Candida albicans
infectious disease
connexin 43
phagosomes
macrophages
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01238-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01238-23

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