Trophoblast retrieval from the cervical canal to predict abnormal pregnancy early in gestation: a pilot study

Abstract Background The current detection of fetal chromosomal abnormalities by non-invasive prenatal testing (NIPT) mainly relies on the cell free DNA(cfDNA) in the maternal blood. However, a gestational age of less than 12 weeks or a high maternal BMI affects cfDNA fetal fraction and further the d...

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Bibliographic Details
Main Authors: Xiaoke Yang, Liuyezi Du, Yue Li, Lin Liang, Linlin Ma, Shaowei Wang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Pregnancy and Childbirth
Subjects:
Online Access:https://doi.org/10.1186/s12884-023-05499-4