Flash drug release from nanoparticles accumulated in the targeted blood vessels facilitates the tumour treatment

Achieving the delivery of drugs into the centre of solid tumours is a challenge due to the tumour micro-environment. Here, the authors propose a system for using the rapid release of large quantities of drug inside tumour microcapillaries for the gradient-driven diffusion of drugs into solid tumours...

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Bibliographic Details
Main Authors: Ivan V. Zelepukin, Olga Yu. Griaznova, Konstantin G. Shevchenko, Andrey V. Ivanov, Ekaterina V. Baidyuk, Natalia B. Serejnikova, Artur B. Volovetskiy, Sergey M. Deyev, Andrei V. Zvyagin
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34718-3