The β3 adrenoceptor in proliferative retinopathies: “Cinderella” steps out of its family shadow

In the retina, hypoxic condition leads to overgrowing leaky vessels resulting in altered metabolic supply that may cause impaired visual function. Hypoxia-inducible factor-1 (HIF-1) is a central regulator of the retinal response to hypoxia by activating the transcription of numerous target genes, in...

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Bibliographic Details
Main Authors: Maurizio Cammalleri, Rosario Amato, Massimo Dal Monte, Luca Filippi, Paola Bagnoli
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Pharmacological Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823000695