Comparative Efficacy of Systemic Agents for Brain Metastases From Non-Small-Cell Lung Cancer With an EGFR Mutation/ALK Rearrangement: A Systematic Review and Network Meta-Analysis

Comparative Efficacy of Systemic Agents for Brain Metastases From Non-Small-Cell Lung Cancer With an EGFR Mutation/ALK Rearrangement: A Systematic Review and Network Meta-Analysis

BackgroundBrain metastases (BM) from non-small-cell lung cancer (NSCLC) are frequent and carry significant morbidity, and current management options include varying local and systemic therapies. Here, we performed a systematic review and network meta-analysis to determine the ideal treatment regimen...

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Bibliographic Details
Main Authors: Shervin Taslimi, Karanbir Brar, Yosef Ellenbogen, Jiawen Deng, Winston Hou, Fabio Y. Moraes, Michael Glantz, Brad E. Zacharia, Aaron Tan, Manmeet S. Ahluwalia, Mustafa Khasraw, Gelareh Zadeh, Alireza Mansouri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Oncology
Subjects:
targeted therapy
brain metastases
non-small cell lung cancer
neuro-oncology
EGFR inhibitors
ALK inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.739765/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.739765/full

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