In-Silico UHPLC Method Optimization for Aglycones in the Herbal Laxatives Aloe barbadensis Mill., Cassia angustifolia Vahl Pods, Rhamnus frangula L. Bark, Rhamnus purshianus DC. Bark, and Rheum palmatum L. Roots

In-Silico UHPLC Method Optimization for Aglycones in the Herbal Laxatives Aloe barbadensis Mill., Cassia angustifolia Vahl Pods, Rhamnus frangula L. Bark, Rhamnus purshianus DC. Bark, and Rheum palmatum L. Roots

For the European Pharmacopoeia (Ph. Eur.) herbal monograph draft of Cassia angustifolia Vahl. and Cassia senna L. leaves and pods, a safety limitation of aloe-emodin and rhein was proposed, due to toxicological concerns. A quantitative, analytical method of the anthraquinone aglycones in all Ph. Eur...

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Bibliographic Details
Main Authors: Nadja Meier, Beat Meier, Samuel Peter, Evelyn Wolfram
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
anthraquinone aglycones
aloe-emodin
rhein
emodin
chrysophanol
physcion
herbal laxatives
ultra high performance liquid chromatography (UHPLC)
design of experiment (DOE)
chromatographic modelling
Online Access:https://www.mdpi.com/1420-3049/22/11/1838

Internet

https://www.mdpi.com/1420-3049/22/11/1838

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