Gossypetin Is a Novel Modulator of Inflammatory Cytokine Production and a Suppressor of Osteosarcoma Cell Growth

Gossypetin Is a Novel Modulator of Inflammatory Cytokine Production and a Suppressor of Osteosarcoma Cell Growth

Osteosarcoma (OS) is a common childhood sarcoma, and its treatment is hindered by adverse effects, chemoresistance, and recurrence. Interleukin (IL)-6 production by tumors plays a significant role in inflammation, carcinogenesis, and metastasis. This study aimed to investigate the antiproliferative...

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Bibliographic Details
Main Authors: Carina Proença, Ana Teresa Rufino, Isabela Santos, Hélio M. T. Albuquerque, Artur M. S. Silva, Eduarda Fernandes, José Miguel P. Ferreira de Oliveira
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Antioxidants
Subjects:
bone sarcoma
chemotherapeutic agents
flavonoid
3,3′,4′,5,7,8-hexahydroxyflavone
apoptosis
proinflammatory cytokines
Online Access:https://www.mdpi.com/2076-3921/12/9/1744

Internet

https://www.mdpi.com/2076-3921/12/9/1744

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