Microfluidic device facilitates in vitro modeling of human neonatal necrotizing enterocolitis–on-a-chip

Microfluidic device facilitates in vitro modeling of human neonatal necrotizing enterocolitis–on-a-chip

Necrotizing enterocolitis (NEC) is a deadly gastrointestinal disease of premature infants that is associated with an exaggerated inflammatory response, dysbiosis of the gut microbiome, decreased epithelial cell proliferation, and gut barrier disruption. We describe an in vitro model of the human neo...

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Bibliographic Details
Main Authors: Wyatt E. Lanik, Cliff J. Luke, Lila S. Nolan, Qingqing Gong, Lauren C. Frazer, Jamie M. Rimer, Sarah E. Gale, Raymond Luc, Shay S. Bidani, Carrie A. Sibbald, Angela N. Lewis, Belgacem Mihi, Pranjal Agrawal, Martin Goree, Marlie Maestas, Elise Hu, David G. Peters, Misty Good
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-04-01
Series:JCI Insight
Subjects:
Cell biology
Inflammation
Online Access:https://doi.org/10.1172/jci.insight.146496

Internet

https://doi.org/10.1172/jci.insight.146496

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