Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers

<p>Abstract</p> <p>Background</p> <p>Epidemiological studies indicate that some characteristics of lung cancer among never-smokers significantly differ from those of smokers. Aberrant promoter methylation and mutations in some oncogenes and tumor suppressor genes are fr...

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Bibliographic Details
Main Authors: Weissfeld Joel L, Siegfried Jill M, Gao Weimin, Liu Yang, Luketich James D, Keohavong Phouthone
Format: Article
Language:English
Published: BMC 2007-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/74