Integrated transcriptome and binding sites analysis implicates E2F in the regulation of self-renewal in human pluripotent stem cells.

Integrated transcriptome and binding sites analysis implicates E2F in the regulation of self-renewal in human pluripotent stem cells.

Rapid cellular growth and multiplication, limited replicative senescence, calibrated sensitivity to apoptosis, and a capacity to differentiate into almost any cell type are major properties that underline the self-renewal capabilities of human pluripotent stem cells (hPSCs). We developed an integrat...

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Bibliographic Details
Main Authors: Hock Chuan Yeo, Thian Thian Beh, Jovina Jia Ling Quek, Geoffrey Koh, Ken Kwok Keung Chan, Dong-Yup Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3208628?pdf=render

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http://europepmc.org/articles/PMC3208628?pdf=render

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