The RNA demethylase ALKBH5 promotes the progression and angiogenesis of lung cancer by regulating the stability of the LncRNA PVT1

The RNA demethylase ALKBH5 promotes the progression and angiogenesis of lung cancer by regulating the stability of the LncRNA PVT1

Abstract Background N6-methyladenosine (m6A) is the most common posttranscriptional modification of RNA and plays critical roles in human cancer progression. However, the biological function of m6A methylation requires further studied in cancer, especially in tumor angiogenesis. Methods A public dat...

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Bibliographic Details
Main Authors: Wenyi Shen, Juan Pu, Zhi Zuo, Shanye Gu, Jing Sun, Bing Tan, Lili Wang, Jianmeng Cheng, Yangsong Zuo
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Cancer Cell International
Subjects:
Lung cancer
ALKBH5
Angiogenesis
PVT1
RNA stability
Online Access:https://doi.org/10.1186/s12935-022-02770-0

Internet

https://doi.org/10.1186/s12935-022-02770-0

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