The two sides of complement C3d: evolution of electrostatics in a link between innate and adaptive immunity.

The interaction between complement fragment C3d and complement receptor 2 (CR2) is a key aspect of complement immune system activation, and is a component in a link between innate and adaptive immunities. The complement immune system is an ancient mechanism for defense, and can be found in species t...

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Bibliographic Details
Main Authors: Chris A Kieslich, Dimitrios Morikis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3531323?pdf=render