Enantioconvergent synthesis of axially chiral amides enabled by Pd-catalyzed dynamic kinetic asymmetric aminocarbonylation
Abstract Atropisomeric biaryls bearing carbonyl groups have attracted increasing attention due to their prevalence in diverse bioactive molecules and crucial role as efficient organo-catalysts or ligands in asymmetric transformations. However, their preparation often involves tedious multiple steps,...
Үндсэн зохиолчид: | , , |
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Формат: | Өгүүллэг |
Хэл сонгох: | English |
Хэвлэсэн: |
Nature Portfolio
2024-08-01
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Цуврал: | Nature Communications |
Онлайн хандалт: | https://doi.org/10.1038/s41467-024-51717-8 |