Predictive value of <i>K-ras</i> and <i>PIK3CA</i> in non-small cell lung cancer patients treated with EGFR-TKIs: a systemic review and meta-analysis

Predictive value of <i>K-ras</i> and <i>PIK3CA</i> in non-small cell lung cancer patients treated with EGFR-TKIs: a systemic review and meta-analysis

<b>Objective:</b>A meta-analysis was performed to augment the insufficient data on the impact of mutative <i>EGFR</i> downstream phosphatidylinositol-3-kinase (<i>PI3K</i>) and mitogen-activated protein kinase (<i>MAPK</i>) pathways on the clinical eff...

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Bibliographic Details
Main Authors: Jie-Ying Chen, Ya-Nan Cheng, Lei Han, Feng Wei, Wen-Wen Yu, Xin-Wei Zhang, Shui Cao, Jin-Pu Yu
Format: Article
Language:English
Published: China Anti-Cancer Association 2015-06-01
Series:Cancer Biology & Medicine
Subjects:
Non-small cell lung cancer (NSCLC)
tyrosine kinase inhibitor (TKI)
targeted therapy
<i>K-ras</i>
<i>PIK3CA</i>
meta-analysis
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/850

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/850

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