Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function
The expression levels of TCRs on the surface of human T cells define the avidity of TCR-HLA/peptide interactions. In this study, we have explored which components of the TCR-CD3 complex are involved in determining the surface expression levels of TCRs in primary human T cells. The results show that...
| Auteurs principaux: | , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Frontiers Media S.A.
2024-05-01
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| Collection: | Frontiers in Immunology |
| Sujets: | |
| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1386132/full |