p38 Mitogen-Activated Protein Kinase Inhibition of Mesenchymal Transdifferentiated Tumor Cells in Head and Neck Squamous Cell Carcinoma

p38 Mitogen-Activated Protein Kinase Inhibition of Mesenchymal Transdifferentiated Tumor Cells in Head and Neck Squamous Cell Carcinoma

High mortality in head and neck squamous cell carcinoma (HNSCC) is due to recurrence, metastasis, and radiochemotherapy (RCT) resistance. These phenomena are related to the tumor cell subpopulation undergoing partial epithelial to mesenchymal transition (pEMT). Repeated transforming growth factor-be...

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Bibliographic Details
Main Authors: Julia Federspiel, Maria do Carmo Greier, Andrea Ladányi, Jozsef Dudas
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomedicines
Subjects:
ralimetinib
SB201290
partial epithelial–mesenchymal transition
cisplatin
head and neck squamous cell carcinoma
Online Access:https://www.mdpi.com/2227-9059/11/12/3301

Internet

https://www.mdpi.com/2227-9059/11/12/3301

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