Increase in <i>TPSB2</i> and <i>TPSD1</i> Expression in Synovium of Hip Osteoarthritis Patients Who Are Overweight

Increase in <i>TPSB2</i> and <i>TPSD1</i> Expression in Synovium of Hip Osteoarthritis Patients Who Are Overweight

While research suggests that increasing body mass index (BMI) is a risk factor for hip osteoarthritis (HOA), the mechanisms of this effect are not fully understood. Tryptases are among the main proteases found in mast cells (MCs) and contribute to OA pathology. <i>TPSB2</i>, which encode...

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Bibliographic Details
Main Authors: Maho Tsuchiya, Kensuke Fukushima, Ken Takata, Yoshihisa Ohashi, Katsufumi Uchiyama, Naonobu Takahira, Hiroki Saito, Ayumi Tsukada, Gen Inoue, Masashi Takaso, Kentaro Uchida
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
hip osteoarthritis
mast cell
obesity
tryptase
Online Access:https://www.mdpi.com/1422-0067/24/14/11532

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https://www.mdpi.com/1422-0067/24/14/11532

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