TERT Promoter Mutations as Simple and Non-Invasive Urinary Biomarkers for the Detection of Urothelial Bladder Cancer in a High-Risk Region

Bladder cancer (BC) is the 10th most common cancer in the world. While there are FDA-approved urinary assays to detect BC, none have demonstrated sufficient sensitivity and specificity to be integrated into clinical practice. Telomerase Reverse Transcriptase (<i>TERT</i>) gene mutations...

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Bibliographic Details
Main Authors: Hamid Pakmanesh, Omid Anvari, Nathalie Forey, Elisabete Weiderpass, Reza Malekpourafshar, Maryam Iranpour, Armita Shahesmaeili, Nahid Ahmadi, Azam Bazrafshan, Kazem Zendehdel, Caroline Kannengiesser, Ibrahima Ba, James McKay, Maria Zvereva, Md Ismail Hosen, Mahdi Sheikh, Florence Le Calvez-Kelm
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/22/14319