CRISPR-Cas9-mediated knockout of CYP79D1 and CYP79D2 in cassava attenuates toxic cyanogen production

CRISPR-Cas9-mediated knockout of CYP79D1 and CYP79D2 in cassava attenuates toxic cyanogen production

Cassava (Manihot esculenta) is a starchy root crop that supports over a billion people in tropical and subtropical regions of the world. This staple, however, produces the neurotoxin cyanide and requires processing for safe consumption. Excessive consumption of insufficiently processed cassava, in c...

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Bibliographic Details
Main Authors: Michael A. Gomez, Kodiak C. Berkoff, Baljeet K. Gill, Anthony T. Iavarone, Samantha E. Lieberman, Jessica M. Ma, Alex Schultink, Nicholas G. Karavolias, Stacia K. Wyman, Raj Deepika Chauhan, Nigel J. Taylor, Brian J. Staskawicz, Myeong-Je Cho, Daniel S. Rokhsar, Jessica B. Lyons
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Plant Science
Subjects:
cassava (Manihot esculenta Crantz)
cyanide
cyanogenesis
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas9 (CRISPR-associated protein 9)
genome editing
CYP79D
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2022.1079254/full

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https://www.frontiersin.org/articles/10.3389/fpls.2022.1079254/full

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