Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells.

The vascular endothelial growth factor (VEGF) family of cytokines are key drivers of blood vessel growth and remodeling. These ligands act via multiple VEGF receptors (VEGFR) and co-receptors such as Neuropilin (NRP) expressed on endothelial cells. These membrane-associated receptors are not solely...

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Bibliographic Details
Main Authors: Sarvenaz Sarabipour, Karina Kinghorn, Kaitlyn M Quigley, Anita Kovacs-Kasa, Brian H Annex, Victoria L Bautch, Feilim Mac Gabhann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011798&type=printable