Modeling the autonomic and metabolic effects of obstructive sleep apnea: A simulation study.

Long term exposure to intermittent hypoxia and sleep fragmentation introduced by recurring obstructive sleep apnea has been linked to subsequent cardiovascular disease and Type 2 diabetes. The underlying mechanisms remain unclear, but impairment of the normal interactions among the systems that regu...

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Bibliographic Details
Main Authors: Limei eCheng, Michael C.K. Khoo
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00111/full