Alkbh5 plays indispensable roles in maintaining self-renewal of hematopoietic stem cells

Alkbh5 plays indispensable roles in maintaining self-renewal of hematopoietic stem cells

Alkbh5 is one of the primary demethylases responsible for reversing N6-methyladenosine (m6A) modifications on mRNAs, and it plays a crucial role in many physiological and pathological processes. Previous studies have shown that Alkbh5 is required for maintaining the function of leukemia stem cells b...

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Bibliographic Details
Main Authors: Yang Bijie, Liu Yuanyuan, Xiao Feifei, Liu Zhilong, Chen Zhe, Li Zhigang, Zhou Chengfang, Kuang Mei, Shu Yi, Liu Shan, Zou Lin
Format: Article
Language:English
Published: De Gruyter 2023-08-01
Series:Open Medicine
Subjects:
hematopoietic stem cells
self-renewal
demethylation
Online Access:https://doi.org/10.1515/med-2023-0766

Internet

https://doi.org/10.1515/med-2023-0766

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