Membrane Guanylyl Cyclase Complexes Shape the Photoresponses of Retinal Rods and Cones

In vertebrate rods and cones, photon capture by rhodopsin leads to the destruction of cyclic GMP (cGMP) and the subsequent closure of cyclic nucleotide gated (CNG) ion channels in the outer segment plasma membrane. Replenishment of cGMP and reopening of the channels limit the growth of the photon re...

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Bibliographic Details
Main Authors: Xiao-Hong eWen, Alexander M Dizhoor, Clint L Makino
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00045/full