Elucidating Role of Reactive Oxygen Species (ROS) in Cisplatin Chemotherapy: A Focus on Molecular Pathways and Possible Therapeutic Strategies

Elucidating Role of Reactive Oxygen Species (ROS) in Cisplatin Chemotherapy: A Focus on Molecular Pathways and Possible Therapeutic Strategies

The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective treatment of cancer patients, it is of great importance to reveal the molecular pathways and mechanisms involved in chemoresistance. Cisplatin (CP) is a platinum-containing drug with anti-tumor activity again...

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Bibliographic Details
Main Authors: Sepideh Mirzaei, Kiavash Hushmandi, Amirhossein Zabolian, Hossein Saleki, Seyed Mohammad Reza Torabi, Adnan Ranjbar, SeyedHesam SeyedSaleh, Seyed Omid Sharifzadeh, Haroon Khan, Milad Ashrafizadeh, Ali Zarrabi, Kwang-seok Ahn
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
cisplatin
reactive oxygen species
drug resistance
chemoresistance
nanoparticles
gene therapy
Online Access:https://www.mdpi.com/1420-3049/26/8/2382

Internet

https://www.mdpi.com/1420-3049/26/8/2382

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