The role of retrograde intraflagellar transport genes in aminoglycoside-induced hair cell death

Sensory hair cells are susceptible to numerous insults, including certain therapeutic medications like aminoglycoside antibiotics, and hearing and balance disorders are often a dose-limiting side effect of these medications. We show that mutations in multiple genes in both the retrograde intraflagel...

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Bibliographic Details
Main Authors: Tamara M. Stawicki, Tor Linbo, Liana Hernandez, Lauren Parkinson, Danielle Bellefeuille, Edwin W. Rubel, David W. Raible
Format: Article
Language:English
Published: The Company of Biologists 2019-01-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/8/1/bio038745