Construction and Immunogenicity of Modified mRNA-Vaccine Variants Encoding Influenza Virus Antigens

Construction and Immunogenicity of Modified mRNA-Vaccine Variants Encoding Influenza Virus Antigens

Nucleic acid-based influenza vaccines are a promising platform that have recently and rapidly developed. We previously demonstrated the immunogenicity of DNA vaccines encoding artificial immunogens AgH1, AgH3, and AgM2, which contained conserved fragments of the hemagglutinin stem of two subtypes of...

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Detaylı Bibliyografya
Asıl Yazarlar: Ekaterina V. Starostina, Sergei V. Sharabrin, Denis N. Antropov, Grigory A. Stepanov, Georgiy Yu. Shevelev, Anna E. Lemza, Andrey P. Rudometov, Mariya B. Borgoyakova, Nadezhda B. Rudometova, Vasiliy Yu. Marchenko, Natalia V. Danilchenko, Anton N. Chikaev, Sergei I. Bazhan, Alexander A. Ilyichev, Larisa I. Karpenko
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: MDPI AG 2021-05-01
Seri Bilgileri:Vaccines
Konular:
mRNA-vaccine
influenza virus
mRNA modification
Anti-Reverse Cap Analog
pseudouridine
N6-methyladenosine
Online Erişim:https://www.mdpi.com/2076-393X/9/5/452

Internet

https://www.mdpi.com/2076-393X/9/5/452

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