Genomic sequencing has a high diagnostic yield in children with congenital anomalies of the heart and urinary system

Genomic sequencing has a high diagnostic yield in children with congenital anomalies of the heart and urinary system

BackgroundCongenital heart defects (CHD) and congenital anomalies of the kidney and urinary tract (CAKUT) account for significant morbidity and mortality in childhood. Dozens of monogenic causes of anomalies in each organ system have been identified. However, even though 30% of CHD patients also hav...

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Bibliographic Details
Main Authors: Erika T. Allred, Elliot A. Perens, Nicole G. Coufal, Erica Sanford Kobayashi, Stephen F. Kingsmore, David P. Dimmock
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pediatrics
Subjects:
genomics
congenital anomalies
kidneys
heart
sequencing
hospital
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1157630/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2023.1157630/full

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