A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants

A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants

Here, Farley et al. perform untargeted lipidomics to assess how SARS-CoV-2 rewires host lipid metabolism. SARS-CoV-2 viral proteins specifically induce lipid droplet formation and dramatically change lipid metabolism to support infection; interfering with lipid metabolism using small molecule inhibi...

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Bibliographic Details
Main Authors: Scotland E. Farley, Jennifer E. Kyle, Hans C. Leier, Lisa M. Bramer, Jules B. Weinstein, Timothy A. Bates, Joon-Yong Lee, Thomas O. Metz, Carsten Schultz, Fikadu G. Tafesse
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31097-7

Internet

https://doi.org/10.1038/s41467-022-31097-7

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