Host-Cell Type Dependent Features of Recombinant Human Aquaporin-4 Orthogonal Arrays of Particles—New Insights for Structural and Functional Studies
The CNS plasma-membrane water channel aquaporin-4 (AQP4) is expressed as two major isoforms able to aggregate into supramolecular assemblies known as ‘orthogonal arrays of particles’ (OAPs). OAP subnanometric features are largely unknown mainly because a method for the expression...
Main Authors: | Francesco Pisani, Laura Simone, Maria Grazia Mola, Manuela De Bellis, Maria Mastrapasqua, Maddalena Ruggieri, Maria Trojano, Grazia Paola Nicchia, Maria Svelto, Antonio Frigeri |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-02-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/2/119 |
Similar Items
-
Aquaporin-4 in Neuromyelitis Optica Spectrum Disorders: A Target of Autoimmunity in the Central Nervous System
by: Yoichiro Abe, et al.
Published: (2022-04-01) -
Astrocyte Aquaporin Dynamics in Health and Disease
by: Maja Potokar, et al.
Published: (2016-07-01) -
Insights into Cell Surface Expression, Supramolecular Organization, and Functions of Aquaporin 4 Isoforms in Astrocytes
by: Jernej Jorgačevski, et al.
Published: (2020-12-01) -
Disassembly and Mislocalization of AQP4 in Incipient Scar Formation after Experimental Stroke
by: Shervin Banitalebi, et al.
Published: (2022-01-01) -
Predominant Myofibrillar Pathology with Preserved Sarcolemmal Aquaporin 4 Immunoreactivity in a Patient with Neuromyelitis Optica-Associated HyperCKemia
by: So-Young Huh, et al.
Published: (2021-12-01)