Methodological challenges in constructing DNA methylation risk scores
Polygenic approaches often access more variance of complex traits than is possible by single variant approaches. For genotype data, genetic risk scores (GRS) are widely used for risk prediction as well as in association and interaction studies. Recently, interest has been growing in transferring GRS...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2020-02-01
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Series: | Epigenetics |
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Online Access: | http://dx.doi.org/10.1080/15592294.2019.1644879 |