Screening for cryptococcal antigenemia and meningeal cryptococcosis, genetic characterization of Cryptococcus neoformans in asymptomatic patients with advanced HIV disease in Kinshasa, Democratic Republic of Congo

Screening for cryptococcal antigenemia and meningeal cryptococcosis, genetic characterization of Cryptococcus neoformans in asymptomatic patients with advanced HIV disease in Kinshasa, Democratic Republic of Congo

Abstract We evaluated the prevalence of serum and meningeal cryptococcosis in asymptomatic outpatients with advanced HIV disease (CD4 < 200 cells/mm3) in a cross-sectional screening context in Kinshasa clinics (DRC). Lumbar puncture (LP) was performed in patients with positive serum cryptococcal...

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Bibliographic Details
Main Authors: Bive Bive Zono, Rosalie Sacheli, Dacquin Muhandwa Kasumba, Hippolyte Nani-Tuma Situakibanza, Alphonse Mavanga, Justin Mwambi Anyshayi, Mamie Etondo, Jérémie Muwonga, Michel Moutschen, Georges Lelo Mvumbi, Marie-Pierre Hayette
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Cryptococcal antigen screening
People living with HIV
Cryptococcosis
Molecular characterization
Antifungal susceptibility testing
DRC
Online Access:https://doi.org/10.1038/s41598-024-80772-w

Internet

https://doi.org/10.1038/s41598-024-80772-w

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