Biodegradable MnO2-based gene-engineered nanocomposites for chemodynamic therapy and enhanced antitumor immunity

Biodegradable MnO2-based gene-engineered nanocomposites for chemodynamic therapy and enhanced antitumor immunity

Immune checkpoint blockade (ICB) is emerging as a promising therapeutic approach for clinical treatment against various cancers. However, ICB based monotherapies still suffer from low immune response rate due to the limited and exhausted tumor-infiltrating lymphocytes as well as tumor immunosuppress...

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Bibliographic Details
Main Authors: Yiru Wang, Ming Wu, Xiaorong Wang, Peiyuan Wang, Zhaoyu Ning, Yongyi Zeng, Xiaolong Liu, Haiyan Sun, Aixian Zheng
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Materials Today Bio
Subjects:
Cell membrane
PD-1
Immune checkpoint blockade
MnO2
Hypoxia
Chemodynamic therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422003295

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http://www.sciencedirect.com/science/article/pii/S2590006422003295

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