3,4-dimethoxychalcone induces autophagy and reduces neointimal hyperplasia and aortic lesions in mouse models of atherosclerosis

3,4-dimethoxychalcone induces autophagy and reduces neointimal hyperplasia and aortic lesions in mouse models of atherosclerosis

Abstract Autophagy inducers can prevent cardiovascular aging and age-associated diseases including atherosclerosis. Therefore, we hypothesized that autophagy-inducing compounds that act on atherosclerosis-relevant cells might have a protective role in the development of atherosclerosis. Here we iden...

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Bibliographic Details
Main Authors: Giulia Cerrato, Carlota Alvarez-Lucena, Allan Sauvat, Yanhua Hu, Sabrina Forveille, Guo Chen, Sylvère Durand, Fanny Aprahamian, Marion Leduc, Omar Motiño, Lisardo Boscá, Qingbo Xu, Oliver Kepp, Guido Kroemer
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06305-x

Internet

https://doi.org/10.1038/s41419-023-06305-x

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