Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy

Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy

Abstract Background Autologous stem cell therapy is a promising strategy for cardiovascular diseases including diabetic cardiomyopathy (DCM), but conclusions from clinical trials were compromised. We assumed that diabetes might induce the dysfunction of stem cells and thus limit its therapeutic effe...

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Bibliographic Details
Main Authors: Ying Wang, Yuying Zhang, Kegong Chen, Jie Liu, Donghong Wu, Yao Cheng, Hongjie Wang, Yanbo Li
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Stem Cell Research & Therapy
Subjects:
Diabetic cardiomyopathy
BMSC
Stem cell
Oxidative stress
SAHH
Online Access:https://doi.org/10.1186/s13287-022-03099-1

Internet

https://doi.org/10.1186/s13287-022-03099-1

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