Acquisition of mixed lineage leukemia rearrangement in a chronic myeloid leukemia patient while on imatinib

Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder with a specific genetic abnormality, the Philadelphia chromosome (Ph) translocation t(9;22)(q34;q11) generating the BCR-ABL1 gene fusion. The role of the Philadelpia chromosome translocation t(9;22)(q34;q11) in CML development is...

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Bibliographic Details
Main Author: Adriana Zámečníkova
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Hematology Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/2560