Gene Therapy: Novel Approaches to Targeting Monogenic Epilepsies

Gene Therapy: Novel Approaches to Targeting Monogenic Epilepsies

Genetic epilepsies are a spectrum of disorders characterized by spontaneous and recurrent seizures that can arise from an array of inherited or de novo genetic variants and disrupt normal brain development or neuronal connectivity and function. Genetically determined epilepsies, many of which are du...

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Bibliographic Details
Main Authors: Kimberly Goodspeed, Rachel M. Bailey, Suyash Prasad, Chanchal Sadhu, Jessica A. Cardenas, Mary Holmay, Deborah A. Bilder, Berge A. Minassian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neurology
Subjects:
genetic epilepsy
AAV9
Lafora
SLC13A5
SLC6A1
gene therapy (GT)
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.805007/full

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https://www.frontiersin.org/articles/10.3389/fneur.2022.805007/full

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