ESSENTIALS: software for rapid analysis of high throughput transposon insertion sequencing data.

High-throughput analysis of genome-wide random transposon mutant libraries is a powerful tool for (conditional) essential gene discovery. Recently, several next-generation sequencing approaches, e.g. Tn-seq/INseq, HITS and TraDIS, have been developed that accurately map the site of transposon insert...

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Bibliographic Details
Main Authors: Aldert Zomer, Peter Burghout, Hester J Bootsma, Peter W M Hermans, Sacha A F T van Hijum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22900082/pdf/?tool=EBI