Divergent Role of Sphingosine 1-Phosphate on Insulin Resistance

Divergent Role of Sphingosine 1-Phosphate on Insulin Resistance

Insulin resistance is a complex metabolic disorder in which insulin-sensitive tissues fail to respond to the physiological action of insulin. There is a strong correlation of insulin resistance and the development of type 2 diabetes both reaching epidemic proportions. Dysfunctional lipid metabolism...

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Bibliographic Details
Main Authors: Susann Fayyaz, Lukasz Japtok, Burkhard Kleuser
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Insulin resistance
Sphingosine 1-phosphate (S1P)
Diacylglycerol (DAG)
Non-esterified fatty acids (NEFA)
Hepatocytes
Pancreatic cells
Skeletal muscle cells
Ceramides
Online Access:http://www.karger.com/Article/FullText/362990

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http://www.karger.com/Article/FullText/362990

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