The AE4 transporter mediates kidney acid-base sensing

Abstract The kidney plays a key role in the correction of systemic acid-base imbalances. Central for this regulation are the intercalated cells in the distal nephron, which secrete acid or base into the urine. How these cells sense acid-base disturbances is a long-standing question. Intercalated cel...

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Bibliographic Details
Main Authors: H. Vitzthum, M. Koch, L. Eckermann, S. L. Svendsen, P. Berg, C. A. Hübner, C. A. Wagner, J. Leipziger, C. Meyer-Schwesinger, H. Ehmke
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38562-x