DYRK2 downregulation in colorectal cancer leads to epithelial–mesenchymal transition induction and chemoresistance

DYRK2 downregulation in colorectal cancer leads to epithelial–mesenchymal transition induction and chemoresistance

Abstract Colorectal cancer (CRC) is among the most prominent causes of cancer-associated mortality in the world, with chemoresistance representing one of the leading causes of treatment failure. However, the mechanisms governing such chemoresistance remain incompletely understood. In this study, the...

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Bibliographic Details
Main Authors:	Chunrong Wu, Guiyin Sun, Fan Wang, Jiangyan Chen, Fangbiao Zhan, Xiaojuan Lian, Jie Wang, Fanbin Weng, Bo Li, Weijun Tang, Jin Quan, Debing Xiang
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-12-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-022-25053-0

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