Activin A and ALK4 Identified as Novel Regulators of Epithelial to Mesenchymal Transition (EMT) in Human Epicardial Cells

Activin A and ALK4 Identified as Novel Regulators of Epithelial to Mesenchymal Transition (EMT) in Human Epicardial Cells

The epicardium, the mesothelial layer covering the heart, is a crucial cell source for cardiac development and repair. It provides cells and biochemical signals to the heart to facilitate vascularization and myocardial growth. An essential element of epicardial behavior is epicardial epithelial to m...

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Bibliographic Details
Main Authors: Esther Dronkers, Tessa van Herwaarden, Thomas J van Brakel, Gonzalo Sanchez-Duffhues, Marie-José Goumans, Anke M Smits
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
epicardium
EMT—epithelial to mesenchymal transition
ALK4
activin A
cardiac repair and regeneration
heart
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.765007/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.765007/full

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