Inhibition of Neovascularization and Tumor Growth, Facilitation of Wound Repair, by Halofuginone, an Inhibitor of Collagen Type I Synthesis
Halofuginone, an inhibitor of collagen α1(I) gene expression was used for the treatment of subcutaneously implanted C6 glioma tumors. Halofuginone had no effect on the growth of C6 glioma spheroids in vitro, these spheroids showed no collagen α1(I) expression and no collagen synthesis. However, a si...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1999-10-01
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| Series: | Neoplasia: An International Journal for Oncology Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558699800232 |