TXNIP/NLRP3 aggravates global cerebral ischemia-reperfusion injury-induced cognitive decline in mice

TXNIP/NLRP3 aggravates global cerebral ischemia-reperfusion injury-induced cognitive decline in mice

Global cerebral ischemia/reperfusion (GCI/R) injury poses a risk for cognitive decline, with neuroinflammation considered pivotal in this process. This study aimed to unravel the molecular mechanisms underlying GCI/R injury and propose a potential therapeutic strategy for associated cognitive defici...

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Bibliographic Details
Main Authors: Chengjie Yang, Jing Mo, Qingmei Liu, Wei Li, Ye Chen, Jianguo Feng, Jing Jia, Li Liu, Yiping Bai, Jun Zhou
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Thioredoxin-interacting protein
Cognitive decline
Neuroinflammation
Global cerebral ischemia/reperfusion injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024034546

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http://www.sciencedirect.com/science/article/pii/S2405844024034546

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