Immunotherapies: The Blockade of Inhibitory Signals
<p>T lymphocytes require signaling by the T cell receptor and by nonclonotypic cosignaling receptors. The costimulatory and inhibitory signals profoundly influence the course of immune responses by amplifying or reducing the transcriptional effects of T cell receptor triggering. The inhibitory...
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Format: | Article |
Language: | English |
Published: |
Ivyspring International Publisher
2012-01-01
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Series: | International Journal of Biological Sciences |
Online Access: | http://www.biolsci.org/v08p1420.htm |