Immunotherapies: The Blockade of Inhibitory Signals

Immunotherapies: The Blockade of Inhibitory Signals

<p>T lymphocytes require signaling by the T cell receptor and by nonclonotypic cosignaling receptors. The costimulatory and inhibitory signals profoundly influence the course of immune responses by amplifying or reducing the transcriptional effects of T cell receptor triggering. The inhibitory...

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Bibliographic Details
Main Author:	Yan-Ling Wu, Jing Liang, Wen Zhang, Yoshimasa Tanaka, Hiroshi Sugiyama
Format:	Article
Language:	English
Published:	Ivyspring International Publisher 2012-01-01
Series:	International Journal of Biological Sciences
Online Access:	http://www.biolsci.org/v08p1420.htm

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