Defining Specific Cell States of MPTP-Induced Parkinson’s Disease by Single-Nucleus RNA Sequencing

Defining Specific Cell States of MPTP-Induced Parkinson’s Disease by Single-Nucleus RNA Sequencing

Parkinson’s disease (PD) is a neurodegenerative disease with an impairment of movement execution that is related to age and genetic and environmental factors. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin widely used to induce PD models, but the effect of MPTP on the cells and...

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Bibliographic Details
Main Authors: Yunxia Guo, Junjie Ma, Hao Huang, Jitao Xu, Chao Jiang, Kaiqiang Ye, Ning Chang, Qinyu Ge, Guangzhong Wang, Xiangwei Zhao
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
single-nucleus RNA sequencing
cellular states
cell–cell communications
Online Access:https://www.mdpi.com/1422-0067/23/18/10774

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https://www.mdpi.com/1422-0067/23/18/10774

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