Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

Abstract Background Cytokines are critical to human disease and are attractive therapeutic targets given their widespread influence on gene regulation and transcription. Defining the downstream regulatory mechanisms influenced by cytokines is central to defining drug and disease mechanisms. One prom...

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Bibliographic Details
Main Authors: Emma E. Davenport, Tiffany Amariuta, Maria Gutierrez-Arcelus, Kamil Slowikowski, Harm-Jan Westra, Yang Luo, Ciyue Shen, Deepak A. Rao, Ying Zhang, Stephen Pearson, David von Schack, Jean S. Beebe, Nan Bing, Sally John, Michael S. Vincent, Baohong Zhang, Soumya Raychaudhuri
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Genome Biology
Subjects:
eQTL
Interactions
Clinical trials
Cytokines
Online Access:http://link.springer.com/article/10.1186/s13059-018-1560-8

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http://link.springer.com/article/10.1186/s13059-018-1560-8

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