Preoptic leptin signaling modulates energy balance independent of body temperature regulation

Preoptic leptin signaling modulates energy balance independent of body temperature regulation

The adipokine leptin acts on the brain to regulate energy balance but specific functions in many brain areas remain poorly understood. Among these, the preoptic area (POA) is well known to regulate core body temperature by controlling brown fat thermogenesis, and we have previously shown that glutam...

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Bibliographic Details
Main Authors: Sangho Yu, Helia Cheng, Marie François, Emily Qualls-Creekmore, Clara Huesing, Yanlin He, Yanyan Jiang, Hong Gao, Yong Xu, Andrea Zsombok, Andrei V Derbenev, Eduardo A Nillni, David H Burk, Christopher D Morrison, Hans-Rudolf Berthoud, Heike Münzberg
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
knockdown
body weight
energy expenditure
food intake
high fat diet
preoptic area
Online Access:https://elifesciences.org/articles/33505

Internet

https://elifesciences.org/articles/33505

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