Exosomal miR-125b-5p derived from adipose-derived mesenchymal stem cells enhance diabetic hindlimb ischemia repair via targeting alkaline ceramidase 2

Exosomal miR-125b-5p derived from adipose-derived mesenchymal stem cells enhance diabetic hindlimb ischemia repair via targeting alkaline ceramidase 2

Abstract Introduction Ischemic diseases caused by diabetes continue to pose a major health challenge and effective treatments are in high demand. Mesenchymal stem cells (MSCs) derived exosomes have aroused broad attention as a cell-free treatment for ischemic diseases. However, the efficacy of exoso...

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Bibliographic Details
Main Authors: Jiahe Guo, Xiaofan Yang, Jing Chen, Cheng Wang, Yue Sun, Chengqi Yan, Sen Ren, Hewei Xiong, Kaituo Xiang, Maojie Zhang, Chengcheng Li, Guoyong Jiang, Xuejiao Xiang, Gui Wan, Tao Jiang, Yu Kang, Xiang Xu, Zhenbing Chen, Wenqing Li
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Nanobiotechnology
Subjects:
Adipose-derived mesenchymal stem cells
Exosomes
miR-125b-5p
Hindlimb ischemia
Alkaline ceramidase 2
Bioinformatics analysis
Online Access:https://doi.org/10.1186/s12951-023-01954-8

Internet

https://doi.org/10.1186/s12951-023-01954-8

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