Persistent Impact of In Utero Irradiation on Mouse Brain Structure and Function Characterized by MR Imaging and Behavioral Analysis

Persistent Impact of In Utero Irradiation on Mouse Brain Structure and Function Characterized by MR Imaging and Behavioral Analysis

Prenatal irradiation is known to perturb brain development. Epidemiological studies revealed that radiation exposure during weeks 8 to 15 of pregnancy was associated with an increased occurrence of mental disability and microcephaly. Such neurological deficits were reproduced in animal models, in wh...

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Bibliographic Details
Main Authors: Tine eVerreet, Janaki Raman Rangarajan, Roel eQuintens, Mieke eVerslegers, Adrian C Lo, Kristof eGovaerts, Mieke eNeefs, Liselotte eLeysen, Sarah eBaatout, Frederik eMaes, Uwe eHimmelreich, Rudi eD'Hooge, Lieve eMooons, Mohammed Abderrafi Benotmane
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Cognition
Microcephaly
MRI
sociability
Brain Development
Radiation exposure
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00083/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00083/full

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